Español 103-112 (Español (España))
FLIP
Authors who publish in this journal agree to the following terms:
Acta Colombiana de Psicología complies with international intellectual property and copyright laws, and particularly with Article No. 58 of the Political Constitution of Colombia, Law No. 23 of 1982, and the Agreement No. 172 of September 30, 2010 (Universidad Católica de Colombia Intellectual Property Regulation).
Authors retain their copyright and grant to the Acta Colombiana de Psicología the right of first publication, with the work registered under Creative Commons attribution license, which allows third parties to use the published material, provided they credit the authorship of the work and the first publication in this Journal.
Abstract
Diurnal cortisol rhythm is affected in patients with cancer. Factors such as disease progression and stress levels are regarded as possible causes of this condition, however results are not clear. The aim of this study was to assess and determine whether there are differences in cortisol levels in women with breast cancer in different stages and analyze the relationship between cortisol levels and stress, optimism and coping strategies. Salivary cortisol samples were collected for two days and psychological questionnaires of perceived stress (PSS), dispositional optimism (LOT-R) and coping strategies (MAC) were administered to 17 breast cancer women in stage I, II and III of the disease. The results show that patients with breast cancer in the three stages have a normal diurnal cortisol rhythm and do not differ significantly in cortisol levels. Regarding the psychological variables, they differ only in the optimism. Coping strategies such as fighting spirit and cognitive avoidance are the variables that have more influence on the cortisol levels, explaining 55% of variance. The implications of these results are discussed.
References
Abercrombie, H., Giese-Davis, J., Sephton, S., Epel, E., Turner- -Cobb, J. & Spiegel, D. (2003). Flattened cortisol rhythms in metastatic breast cancer patients. Psychoneuroendocrinology, 29, 1082–1092.
Barroilhet, S., Forjaz, M. & Garrido, E. (2005). Conceptos, teorías y factores psicosociales en la adaptación al cáncer. Actas Españolas de Psiquiatría, 33(6), 390-397.
Bigatti, S., Steiner, J. & Miller, K. (2012). Cognitive Appraisals, Coping and Depressive Symptoms in Breast Cancer Patients. Stress and Health, 28, 355-361.
Carlson, L., Campbell, T., Garland, S. & Grossman, P. (2007). Associations among salivary cortisol, melatonin, catecholamines, sleep quality and stress in women with breast cancer and healthy controls. Journal of Behavioral Medicine, 30(1), 45-58.
Cohen, S., Kamarak, T. & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 24, 385-396.
Cordova, M., Giese-Davis, J., Golant, M., Kronnenwetter, C., Chang, V., McFarlin, S. & Spiegel, D. (2003). Mood disturbance in community cancer support groups: The role of emotional suppression and fighting spirit. Journal of Psychosomatic Research, 55, 5, 461–467.
Costanzo, E., Lutgendorf, S., Rothrock, N. & Anderson, B. (2006). Coping and quality of life among women extensively treated for gynecologic cancer. Psycho-Oncology, 15, 132-142.
Coyne, J. & Tennen, H. (2010). Positive Psychology in Cancer Care: Bad Science, Exaggerated Claims and Unproven Medicine. Annals of Behavioral Medicine, 39, 16–26.
Dedert, E., Lush, E., Chagpar, A., Dhabhar, F., Segestrom, S., Spiegel, D., Dayyat, E., Daup, M., McMasters, K. & Sephton, S. (2012). Stress, Coping, and Circadian Disruption Among Women Awaiting Breast Cancer Surgery. Annals of Behavioral Medicine, 44(1), 10-20.
Dettenborn, L., James, G., Valdimarsdottir, H., Montgomery, G. & Bovbjerg, D. (2006). Breast cancer-specific intrusions are associated with increased cortisol responses to daily life stressors in healthy women without personal or family histories of breast cancer. Journal of Behavioral Medicine, 29(5), 477-485.
Donovan-Kicken, E. & Caughlin, J. (2011). Breast cancer patients’ topic avoidance and psychological distress: The mediating role of coping. Journal of Health Psychology, 16(4): 596-606.
Fan, Y., Tang, Y., Lu, Q., Feng, S., Yu, Q., Sui, D., Zhao, Q., Ma, Y. & Li, S. (2009). Dynamic changes in salivary cortisol and secretory immunoglobulin A response to acute stress. Stress and Health, 25, 189-194.
Fekedulegn, D. Andrew, M., Burchfiel, C., Violanti, J., Hartley, T., Charles, L.E. & Miller D.B. (2007). Area under the curve and other summary indicators of repeated waking cortisol measurements. Psychosomatic Medicine, 69, 651–665.
Fischbach, F. & Dunning, M. (2009). A manual of laboratory and diagnostic test. Ed 8. China: Wolters Kluwer Health/ Lippincott Williams and Wilkins.
Fries, E., Hesse, J., Hellhammer, J. & Hellhammer, D. (2005). A new view on hypocortisolisms. Psychoneuroendocrinology, 30(10), 1010–1016.
Folkman, S. & Moskowitz, J. (2004). COPING: Pitfalls and Promise. Annual Review of Psychology, 55(1), 745-774. doi:10.1146/annurev.psych.55.090902.141456.
Garland, M., Lavelle, E., Doherty, D., Golden-Mason, L., Fitzpatrick, P., Hill, A., Walsh, N. & O’ Farrely, C. (2004). Cortisol does not mediate the suppressive effects of psychiatric morbidity on natural killer cell activity: A cross-sectional study of patients with early breast cancer. Psychological Medicine, 34, 481- 490.
González, M. & Landero, R. (2007). Factor structure of the perceived stress scale (PSS) in a sample from México. The Spanish Journal of Psychology, 10(1): 199-206.
Haus, E., Dumitriu, L., Nicolau, G., Bogola, S. & SackaettLunden, L. (2001). Circadian Rhythms of basic fibroblast growth factor (bFGF), epidermal growth factor (EGF), insulin-like growth factor-1 (IGG-1), insulin-like growth factor binding protein-3 (IGFBP-3) cortisol and melatonin in women with breast cancer. Chronobiology International, 18(4), 709-727.
Kronfol, Z., Nair, M., Zhang, Q., Hill, E. & Brown, M. (1997). Circadian immune measures in healthy volunteers: Relationship to hypothalamic-pituitary-adrenal axis hormones and sympathetic neurotransmitters. Psychosomatic Medicine, 59, 42-50.
Lang, E., Berbaum, K. & Lutgendorf, S. (2009). Large-Core Breast Biopsy: Abnormal Salivary Cortisol Profiles Associated with Uncertainty of Diagnosis. Radiology, 250(3), 631-637.
Lazarus, R. (2000). Estrés y Emoción: Manejo e implicaciones en nuestra salud. Bilbao: Descleé de Brower.
Lissoni, P., Brivio, F., Fumagalli, L., Messina, G., Secreto, G., Romelli, B., & Brera, G. (2007). Immune and endocrine mechanisms of advanced cancer-related hypercortisolemia. In vivo, 21(4), 647-650.
Master, S., Amodio, D., Stanton, A., Yee, C., Hilmert, C. & Taylor, S. (2009). Neurobiological Correlates of Coping through Emotional Approach. Brain, Behavior and Immunity, 23(1), 27-35.
McEwen, B. (2007). Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain. Physiological Review, 87, 873–904, doi:10.1152/physrev.00041.2006.
Mazzoccoli, G., Giuliani, F. & Sothern, R. (2012). Determination of whole body circadian phase in lung cancer patients: melatonin vs. cortisol. The International Journal of Cancer Epidemiology, Detection, and Prevention, 36, 46-53.
Mazzoccoli, G., Tarquini, R., Durfot, T. & Francois, J. (2011). Chronodisruption in lung cancer and possible therapeutic approaches. Biomedicine and Pharmacotherapy, 65, 500– 508.
Mazzoccoli, G., Vendemiale, G., De Cata, A., Carughi, S. & Tarquini, R. (2010). Altered time structure of neuro-endocrine-immune system function in lung cancer patients. BMC Cancer, 10, 314. Doi:10.1186/1471-2407-10-314.
Morrow, G., Hickok, J., Andrews, P. & Stern, R. (2002). Reduction in serum cortisol after platinum based chemotherapy for cancer: A role for the HPA axis in treatment-related nausea. Psychophysiology, 39(4), 491-495.
Moscoso, M. (2009). De la mente a la célula: Impacto del estrés en psiconeuroinmunoendocrinología. LIBERABIT, 15(2), 143-152.
Nakaya, N., Fukudo, S., Akizuki, N., Yoshikawa, E., Kobayakawa, M., Fujimori, M., ... & Uchitomi, Y. (2005). Twenty-four-hour urinary cortisol levels before complete resection of non-small cell lung cancer and survival. Acta Oncologica, 44(4), 399-405.
Otero, J., Luengo, A., Romero, E., Gómez, J. & Castro, C. (1998). Psicología de personalidad. Manual de prácticas. Barcelona: Ariel Practicum.
O’Donnell, K., Badrick, E., Kumari, M. & Steptoe, A. (2008). Psychological coping styles and cortisol over the day in healthy older adults. Psychoneuroendocrinology 33(5), 601–611.
Porter, L., Mishel, M., Neelon, V., Belyea, M., Pisano, E. & Scott, M. (2003). Cortisol levels and responses to mammography screening in breast cancer survivors: A pilot study. Psychosomatic Medicine, 65, 842-848.
Powell, D., Liossi, C., Moss-Morris, R. & Schlotz, W. (2013). Unstimulated cortisol secretory activity in everyday life and its relationship with fatigue and chronic fatigue syndrome: A systematic review and subset meta-analysis. Psychoneuroendocrinology, 38, 2405-2422
Pruessner, J., Kirshbaum, C., Meinlschmid, P. & Hellhammer, D. (2003). Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change. Psychoneuroendrocrinology, 28, 916-931.
Putman, P. & Roelofs, K. (2011). Effects of single cortisol administrations on human affect reviewed: Coping with stress through adaptive regulation of automatic cognitive processing. Psychoneuroendocrinology, 36, 439-448
Raedler, T., Jahn, H., Goedeken, B., Gescher, D., Kellner, M. & Wiedemann, K. (2003). Acute effects of megestrol on the hypothalamic–pituitary–adrenal axis. Cancer Chemotherapy and Pharmacology, 52, 482–486. doi 10.1007/s00280- 003-0697-6.
Rosal, M., King, J., Yunsheng, M. & Reed, G. (2004). Stress, Social Support, and Cortisol: Inverse Associations. Behavioral Medicine, 30, 11-21.
Salimetrics, LLC. (2012). Collecting Saliva. Recuperado el 30 de agosto de 2012, desde http://www.salimetrics.com/literature.
Salimetrics, LLC. (2013). Salivary Cortisol. Enzime Immunoassay Kit. Recuperado el 7 de enero de 2014 desde http://www.salimetrics.com/documents/1-3002.pdf
Scheier, M., Carver, C. & Bridges, M. (1994). Distinguishing optimism from neuroticism (and trait anxiety, self-mastery and self-esteem): A reevaluation of the Life Orientation Test. Journal of Personality and Social Psychology, 67(6), 1063-1078.
Schrepf, A., Clevenger, L., Christensen, D., DeGeest, K., Bender, D., Ahmed, A., ... & Lutgendorf, S. K. (2013). Cortisol and inflammatory processes in ovarian cancer patients following primary treatment: Relationships with depression, fatigue, and disability. Brain, behavior, and immunity, 30, S126-S134.
Schoofs, D., Hartmann, R. & Wolf, O. (2008). Neuroendocrine stress response to an oral academic examination: No strong influence of sex, repeated participation and personality traits. Stress, 11(1), 52-61.
Spiegel, D. (2001). Mind matters: Coping and cancer progression. Journal of Psychosomatic Research, 50, (5), 287–290.
Septhon, S., Lush, E., Dedert, E., Floyd, A., Rebholz, W., Dhabhar, F., Spiegel, D. & Salmon, P. (2012). Diurnal cortisol rhythm as a predictor of lung cancer survival. Brain, Behavior and Immunity, 30, 163-170. DOI: 10.1016/j. bbi.2012.07.019.
Sephton, S., Sapolsky, R., Kraemer, H. & Spiegel, D. (2000). Diurnal cortisol rhythm as a predictor of breast cancer survival. Journal of the National Cancer Institute, 92(12), 994- 1000.
Sephton, S. & Spiegel, D. (2003). Circadian disruption in cancer: A neuroendocrine-immune pathway from stress to disease? Brain, Behavior and Immunity, 17, 321-328.
Solberg, L., Segerstrom, S. & Septhon, S. (2005). Engagement and Arousal: Optimism’s Effects During a Brief Stressor. Personality and Social Psychology Bulletin, 31(1), 111-120.
Sjögren, E., Leanderson, P. & Kristenson, M. (2006). Diurnal cortisol levels and relations to psychosocial factors in a population sample of middle-age Swedish men and women. International Journal of Behavioral Medicine, 13(3), 193-200
Taylor, S., Burklund, L., Eisenberger, N., Lehman, B., Hilmert, C. & Lieberman, M. (2008). Neural bases of moderation of cortisol stress responses by psychosocial resources. Journal of Personality and Social Psychology, 95(1), 197-211.
Touitou, Y., Bogdan, A., Lévi, F., Benavides, M. & Auzéby, A. (1996). Disruption of the circadian patterns of serum cortisol in breast and ovarian cancer patients: Relationships with tumor marker antigens. British Journal of Cancer, 74, 1248-1252.
Touitou, Y., Lévi, F., Bogdan, A., Benavides, M., Bailleul, F. & Misset, J. (1995). Rhythm alteration in patients with metastatic breast cancer and poor prognostic factors. Journal Cancer Research Clinic Oncology, 121, 181-188.
Vedhara, K., Miles, J., Bennett, P., Plummer, S., Tallon, D., Brooks, E., ... & Farndon, J. (2003). An investigation into the relationship between salivary cortisol, stress, anxiety and depression. Biological psychology, 62(2), 89-96.
Vedhara, K., Tuin, J., Miles, J., Sanderman, R. & Ranchor, A. (2006). Psychosocial factors associated with indices of cortisol production in women with breast cancer and controls. Psychoneuroendocrinology, 31, 299-311.
Watson, M., Greer, S., Young, J., Inayat, Q., Burgesss, G. & Robertson, B. (1988). Development of questionnaire measure of adjustment to cancer: the MAC scale. Psychological Medicine, 18, 203-206.
Watson, M., Haviland, J., Davidson, J. & Bliss, J. (2000). Fighting spirit in patients with cancer. Lancet, 355, 4, 848, Weinrib, A. Z., Sephton, S. E., DeGeest, K., Penedo, F., Bender, D., Zimmerman, B., ... & Lutgendorf, S. K. (2010). Diurnal cortisol dysregulation, functional disability, and depression in women with ovarian cancer. Cancer,116(18), 4410-4419.
Wüst, S., Federenko, I., Van Rossum, E., Koper, J. & Hellhammer, D. (2005). Habituation of cortisol responses to repeated psychosocial stress-further characterization and impact of genetic factors. Psychoneuroendocrinology, 30(2), 199-211.
Young, C. & Welsh, J. (2005). Stress, Health and Disease: A Review. Cell Science, 2(2), 132-158.
Reference by
